Polystyrene sulfonates are given by mouth ( with a meal ) or rectally, by retention enema.
2.
The pharmacokinetics of rhein have not been intensively studied in humans, but at least one study in healthy male volunteers found that rhein was better absorbed from oral administration of rhubarb than from a retention enema.
3.
He said that a crude extract of the raw fruit and leaves of bitter melon can be taken orally and rectally, but it is recommended that a rectal retention enema be administered daily due to the sensitivity of the juice and extracts when encountering stomach acids.
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